WeLoveDoctor

Category: 03_Study

  • Guidelines for Pathologic Diagnosis of Malignant Mesothelioma 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group1

    1.
    Husain A, Colby T, Ordóñez N, et al. Guidelines for Pathologic Diagnosis of Malignant Mesothelioma 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group. Arch Pathol Lab Med. 2018;142(1):89-108. [PubMed]

  • GATA3: A Multispecific But Potentially Useful Marker in Surgical Pathology A Systematic Analysis of 2500 Epithelial and Nonepithelial Tumors1

     

    1.
    Miettinen M, McCue P, Sarlomo-Rikala M, et al. GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors. Am J Surg Pathol. 2014;38(1):13-22. [PubMed]

  • Next-Generation Sequencing to Diagnose Suspected Genetic Disorders1

    임상에서 NGS 도입과 관련된 review 기사임. 종양 부분이 없다는게 아쉬움.

    1.
    Adams D, Eng C. Next-Generation Sequencing to Diagnose Suspected Genetic Disorders. N Engl J Med. 2018;379(14):1353-1362. [PubMed]

  • Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia1

    CLL 환자에서 한 연구. intron 영역의 polyadenylation 이 mRNA 발현에 영향을 주어 truncated mRNA 발현이 증가하였음. 그리고 이러한 mRNA 들이 tumor suppressor gene 의 역할을 억제하는 효과가 있음. 유전자 발현을 조절하는 기전의 새로운 발견.

    1.
    Lee S, Singh I, Tisdale S, Abdel-Wahab O, Leslie C, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018;561(7721):127-131. [PubMed]