Labial salivary gland biopsy in Sjogren’s disease

Grade            Lymphocytes per 4 sq mm of Salivary Tissue

0                   Absent
1                   Slight infiltrate
2                   Moderate infiltrate or less than one focus’
3                   One focus
4                   More than one focus
‘Focus = an aggregate of 50 or more lymphocytes and histiocytes.

Reference: Chisholm DM, Mason DK. Labial salivary gland biopsy in Sjogren’s disease. J Clin Pathol 1968; 21: 656-60.