WeLoveDoctor

Tag: grade

  • Histopathological grading of ascending aortic aneurysm

    Histopathological grading of ascending aortic aneurysm


    세상은 넓고 옵세는 많다. Aorta 에 대한 degeneration 부분에 대한 것도 등급을 매겨본 사람이 있다. 1년에 한 번 미만으로 사용하는 grade system.

    Reference: Matthias Bechtel JF, Noack F, Sayk F, Erasmi AW, Bartels C, Sievers HH. Histopathological grading of ascending aortic aneurysm: comparison of patients with bicuspid versus tricuspid aortic valve. J Heart Valve Dis. 2003;12(1):54-9; discussion 9-61.

  • Esophagus 에서 Regression grade

    Criteria for evaluation of therapeutic efficacy
    Grade 0: Ineffective

    There is no discernible therapeutic effect on cancer tissue or cells.


    Grade 1: Slightly effective

    Apparently “viable” cancer cells (including cells having eosinophilic cytoplasm with vacuolation and swollen nuclei) account for 1/3 or more of tumor tissue, but there is some evidence of degeneration of cancer tissue or cells.

    Grade 1a: viable cancer cells accounting for 2/3 or more of tumor tissue
    Grade 1b: viable cancer cells accounting for 1/3 or more, but less than 2/3, of tumor tissue

    Grade 2: Moderately effective


    “Viable” cancer cells account for less than 1/3 of tumor tissue, while other cancer cells are severely degenerate or necrotic.

    Grade 3: Markedly effective

    There are no viable cancer cells evident.


    대장암에서 수술전 항암화학요법을 받았을 경우 이에대한 치료 반응 정도를 평가하는 등급은 AJCC 에서도 언급이 되어 있을만큼 일반적으로 받아들여지는 기준이 있다. 하지만, 식도에서는 널리 받아들여지는 기준은 아직 없는 것 같고, 작년 12월에 관련 논문을 찾은 적이 있다.

    Reference: Guidelines for clinical and pathologic studies on carcinoma of the esophagus, ninth edition: part II. Esophagus 2004; 1(3): 107-125. (PubMed 에서 검색이 안됨)

  • Fuhrman Grading System

    Fuhrman Grading System
    . Grade X (GX): Cannot be assessed
    . Grade 1 (G1): Nuclei round, uniform, approximately 10 um in diameter; nucleoli inconspicuous or absent
    . Grade 2 (G2): Nuclei slightly irregular, approximately 15 um in diameter; nucleoli evident
    . Grade 3 (G3): Nuclei very irregular, approximately 20 um in diameter; nucleoli large and prominent
    . Grade 4 (G4): Nuclei bizarre and multilobated, 20 um or greater in diameter, nucleoli prominent, chromatin
    clumped

      막상 책에서 찾으려고 하면 잘 나오지 않는 것 중의 하나…

    Reference:
    1. Srigley JR, Amin MB, Delahunt B, et al. Protocol for the examination of specimens from patients with invasive carcinoma of renal tubular origin. Arch Pathol Lab Med 2010; 134: e25-30.

  • Maceration grade

      이 Grade에 관한 것을 찾으려고 몇 번을 시도했었는데 드디어 찾았다. 🙂 가끔씩 Grade III  상태의 태아를 보내는데 좀.. -_-;; 님하..

    Grade 0
      skin often has a parboiled appearance

    Grade I
      skin starts to peel

    Grade II
      peeling may be extensive and red effusion present in the serous cavities

    Grade III
      the liver is yellowish-brown and the effusions turbid

    Reference: Langley FA. The perinatal postmortem examination. J Clin Pathol1971 Mar;24(2):159-69.